The Mutagenic Potential of: (E)-1,2,3,4-tetrahydro-6-methyl-1(2-methyl-1-oxo-2-butenyl)quinoline 1,2,3,4,-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl)quinoline 50% DEET, 25% Dow Corning 200 Fluid, in Isopropanol

摘要

The mutagenic potential of (E)-1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5); 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl)quinoline (CHR6); 50% DEET, 25% Dow Corning 200 Fluid, in isopropanol (CHF1); was assessed using the Ames/Salmonella Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537, and TA 1538, were exposed to 1 u1/plate through .000032 u1/plate doses of CHR5 and CHR6 and 0.1 u1/plate through .000032 u1/plate doses of CHF1. No evidence of mutagenic activity was observed. (Author)