Medical Applications of Radiofrequency-Radiation Hyperthermia.

摘要

This report provides an overview of the medical applications of radiofrequency radiation (RFR) hyperthermia. RFR has limitations in focusing and penetration but can heat tissue selectively, on the basis of water content and dielectric properties. nonionizing electromagnetic radiation may operate through several mechanisms, which are determined by the amount of energy deposited in tissues and the type of tissue irradiated. These attributes imply great versatility in the clinical applications of RFR. Furthermore, the synergistic activity of RFR with ionizing radiation and chemotherapy in cancer treatment increases their effectiveness at lower doses. Lowered toxicity is a direct consequence of a lower effective dose in the presence of RFR. With improved therapeutic instrumentation and dosimetry and a better understanding of bioeffect mechanisms, the number of medical applications and the effectiveness fof RFR should continue to increase. (Author)