Mutagenic Potential of: 4-Nitrophenyl Dimethyl Phosphinate (TA007) using the Sex-Linked Recessive Lethal Test in Drosophila melanogaster.

摘要

4-Nitrophenyl dimethyl phosphinate (TA007) has a potential as a prophylactic agent in nerve agent poisoning. Mutagenic activity of this compound was assayed using the Sex-Linked Recessive Lethal test in Drosophila melanogaster. TA007 was determined to be non-mutagenic following 72-hour feeding exposures to 0.01 and 0.005 mM concentrations.