Acute Dermal Toxicity Potential of the Holston Compounds: Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge in Male and Female Rabbits

摘要

The acute dermal toxicity potential of the Holston Compounds (Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge) was determined in rabbits by topical application to skin sites with plastic covering over the exposed areas for 24 hours. There were no compound-related deaths at a limit dose of 2 ml/kg during this study. The Holston Compounds caused minimal dermal irritation.