Regiospecific Preparation of alpha, alpha-Dihalofluoromethyl Perfluoroalkyl Ketones

摘要

Acylation of F-phosphoranium salts with F-acyl chlorides gives the corresponding Z-perfluoro betaine in high yield. Subsequent chlorination or bromination regiospecifically yields the alpha,alpha-dihalofluoromethyl perfluoroalkyl ketones.