Skin Sensitization of the Insecticide Permethrin in Man and the Potential for Nonimmunological Contact Urticaria, September 1984 - December 1985

摘要

The insecticide permethrin was tested in man for skin irritation and sensitization using the prophetic patch test. The potential for nonimmunological contact urticaria was also tested using the guinea pig as the predictive model. The results of both tests were negative. It is recommended that permethrin be approved for further evaluation in man as a clothing impregnant at concentrations of 0.125 mg/sq.cm., or less, but that subjects be closely monitored for adverse skin effects.