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WDR26 in Advanced Breast Cancer: A Novel Regulator of the P13K/AKT Pathway.

机译：高级乳腺癌中的WDR26：p13K / aKT途径的新型调节剂。

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Chen, S.;
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年度 2017
页码 1-7
总页数 7
原文格式 PDF
正文语种 eng
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Breast cancer growth and Metastasis; Heterotrimeric G protein; G protein-coupled receptors; Signal transduction; P13K; AKT;

机译：乳腺癌生长和转移;异三聚体G蛋白; G蛋白偶联受体;信号转导; p13K; aKT;

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1. Aberrant methylation of breast and ovarian cancer susceptibility gene 1 in chemosensitive human ovarian cancer cells does not involve the phosphatidylinositol 3'-kinase-Akt pathway. [J] . Wang YQ, Zhang JR, Li SD, Cancer science. . 2010,第7期

机译：化学敏感性人类卵巢癌细胞中乳腺癌和卵巢癌敏感性基因1的异常甲基化不涉及磷脂酰肌醇3'-激酶-Akt途径。
2. Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway. [J] . Morgan TM, Koreckij TD, Corey E Current cancer drug targets . 2009,第2期

机译：晚期前列腺癌的靶向治疗：PI3K / Akt / mTOR途径的抑制。
3. 3-Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl-1 through the PI3K/Akt signaling pathway. [J] . Zhe Liu, Yuan-Yuan Zhang, Qian-Wen Zhang, Anti-cancer drugs . 2014,第4期

机译：3-溴丙酮酸通过PI3K / Akt信号通路下调Mcl-1诱导乳腺癌细胞凋亡。
4. Parallel Reaction Monitoring Assays for Phosphorylation Sites of AKT Isoforms in Patient-Derived Breast Cancer Xenografts with PI3K-AKT Pathway Aberrations [C] . Matthew R. Meyer, Petra Erdmann-Gilmore, Kelly V. Ruggles, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：具有PI3K-AKT路径畸变的患者衍生的乳腺癌异种移植物中AKT同种型的磷酸化位点的平行反应监测测定
5. Sensitivity of MCF-7 breast cancer cells to anticancer drugs is decreased by activation of the PI3K/PDK/Akt signal transduction pathway. [D] . Navolanic, Patrick M. 2004

机译：通过激活PI3K / PDK / Akt信号转导途径，MCF-7乳腺癌细胞对抗癌药物的敏感性降低。
6. Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations and/or PTEN loss/PTEN mutation [O] . Yan Xing, Nancy U. Lin, Matthew A. Maurer, 2019

机译：AKT抑制剂MK-2206在患有PIK3CA或AKT突变和/或PTEN缺失/ PTEN突变的晚期乳腺癌患者中进行的II期临床试验
7. Src Inhibition Can Synergize with Gemcitabine and Reverse Resistance in Triple Negative Breast Cancer Cells via the AKT/c-Jun Pathway. [O] . Zhen-Hua Wu, Chen Lin, Ming-Ming Liu, 2016

机译：src抑制可以通过aKT / c-Jun途径与吉西他滨和三阴性乳腺癌细胞中的抗逆性相协调。

WDR26 in Advanced Breast Cancer: A Novel Regulator of the P13K/AKT Pathway.

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