Enhanced Detection of Biological Threat Agents by Immobilizing Capture AntibodyDirectly onto the Membrane Tape

摘要

This report summarizes the technical work performed on the referenced developmentprogram (Contract No. DAAA15-91-C-0074) over a period of 16 months. The research involved the immobilization of antibody directly onto various membranes. These antibody-immobilized membranes were used to enhance the sensitivity and/or dynamic range of assays developed for the detection of biological threat agents. The results of this research program are reviewed in an executive summary, followed by a statement of the purpose and objectives of the research. The report addresses each of these objectives and includes results and discussion, materials, methods, conclusions, and recommendations. MS2, AbCoatTM, LAPS system, SEB, Anti(SEB), StabilCoat, Threshold, Rabbit IgG.