Solubilities of Nitrogen and Helium in Water and Blood at 37 deg C and Pressuresof Up to 11 ATA

摘要

The solubilities of N2 and He in water and whole blood were measured at 37 deg Cusing a barometric method described in an earlier report (NMRI Technical Report 90-138). Solubilities have been measured successfully in H2O at approx. 2 ATA and approx. 11 ATA. In addition, protocols for measuring solubilities in whole blood have been explored. Measurements in blood have been unsuccessful thus far (i.e., have disagreed with published results), apparently because efforts have failed to eliminate interphase transport of the metabolic gases O2 and CO2 during the experiment. Blood experiments can resume after the experimental assembly has been modified to allow sampling of the gas phase so that its composition can be determined. This information, in conjunction with the pressure measurements that already are made during each experiment, will enable one to eliminate the confounding effect of O2 and CO2 transport.