Charlie Laughton is Associate Professor and Reader in Molecular Recognition in the School of Pharmacy, University of Nottingham. His doctorate was in synthetic organic chemistry, but for the last twenty years he has worked primarily on the development and application of simulation methodologies to problems in biomolecular While the first molecular dynamics (MD) simulations of proteins were reported by McCammon and Karplus between 1976 and 1977, the first reports of simulations of nucleic acids were not until seven years later: of double-helical DNA by the Levitt and Karplus groups and of tRNA by the McCammon and Harvey groups.
展开▼
