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A framework for organ dose estimation in x-ray angiography and interventional radiology based on dose-related data in DICOM structured reports

机译:基于DICOM结构化报告中剂量相关数据的X射线血管造影和介入放射学中器官剂量估算的框架

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Although interventional x-ray angiography (XA) procedures involve relatively high radiation doses that can lead to deterministic tissue reactions in addition to stochastic effects, convenient and accurate estimation of absorbed organ doses has traditionally been out of reach. This has mainly been due to the absence of practical means to access dose-related data that describe the physical context of the numerous exposures during an XA procedure. The present work provides a comprehensive and general framework for the determination of absorbed organ dose, based on non-proprietary access to dose-related data by utilizing widely available DICOM radiation dose structured reports. The framework comprises a straightforward calculation workflow to determine the incident kerma and reconstruction of the geometrical relation between the projected x-ray beam and the patient's anatomy. The latter is difficult in practice, as the position of the patient on the table top is unknown. A novel patient-specific approach for reconstruction of the patient position on the table is presented. The proposed approach was evaluated for 150 patients by comparing the estimated position of the primary irradiated organs (the target organs) with their position in clinical DICOM images. The approach is shown to locate the target organ position with a mean (max) deviation of 1.3 (4.3), 1.8 (3.6) and 1.4 (2.9) cm for neurovascular, adult and paediatric cardiovascular procedures, respectively. To illustrate the utility of the framework for systematic and automated organ dose estimation in routine clinical practice, a prototype implementation of the framework with Monte Carlo simulations is included.
机译:尽管介入X射线血管造影(XA)程序涉及相对较高的辐射剂量,除了随机效应之外,这还可能导致确定性的组织反应,但传统上无法方便,准确地估算吸收的器官剂量。这主要是由于缺乏实用的方法来访问剂量相关的数据,这些数据描述了XA程序中大量暴露的物理环境。本工作通过利用广泛使用的DICOM辐射剂量结构化报告非专有地获取剂量相关数据,为确定吸收的器官剂量提供了一个全面而通用的框架。该框架包括一个简单的计算工作流程,用于确定入射比释动能,并重建投影的X射线束与患者解剖结构之间的几何关系。后者在实践中是困难的,因为患者在桌面上的位置是未知的。提出了一种新颖的特定于患者的方法,用于重建患者在桌子上的位置。通过比较主要受辐照器官(目标器官)的估计位置与其在临床DICOM图像中的位置,对150名患者评估了所建议的方法。结果表明,该方法可以定位目标器官位置,神经血管,成人和儿科心血管手术的平均(最大)偏差分别为1.3(4.3),1.8(3.6)和1.4(2.9)cm。为了说明该框架在常规临床实践中用于系统和自动器官剂量估计的实用性,包括了采用蒙特卡洛模拟的框架原型实现。

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