Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

摘要

The Summary In our current adult CF population, low BMD prevalence was only 20 %, lower than that historically described. We found a mild increase of serum RANK-L levels, independent from the bone resorption level. The increased fracture risk in CF may be explained by a lower tibial cortical thickness and total vBMD.