One-pot cyclothiomethylation of amines as efficient method for the synthesis of saturated five-, six-, seven-, and eight-membered S,N-Heterocycles

摘要

The review generalizes and systemizes published data on the synthesis of biologically active saturated five-, six-, seven-, and eight-membered S,N-heterocycles. Particular attention is given to cyclothiomethylation of various amines by the action of two-component systems CH2O-H2S (or thiols) and RCHO-CS2 (or S2Cl2).