Aminomethylation of Phenylacetylene under Microwave Irradiation

摘要

The procedure of Mannich aminomethylation of acetylenes is being permanently improved due to the great practical significance of the resulting products.According to Gevorkyan et al.[1],the principal disadvantage of this reaction is its long time,which was explained by the necessity of using a solvent.The referees carried out aminomethylation of phenylacetylene in the absence of solvent,which allowed the reaction time to be decreased from 60 to 4-6 h.