Acylation of Meldrum's acid with arylacetic acid imidazolides as a convenient method for the synthesis of 4-aryl-3-oxobutanoates

摘要

C-Acylation of Meldrum's acid by (het)arylacetic acids in ethanol in the presence of 1, 1'-carbonyldiimidazole leads to ethyl 4-(het)aryl-3-oxobutanoates in high yields.