Nitropyrazoles 14. Synthesis of 1,3,4-trinitropyrazole and its behavior in the nucleophilic substitution reactions General method of synthesis of 5-substituted 3,4-dinitropyrazoles

摘要

For the first time pyrazole containing three nitro groups in the pyrazole cycle, viz., 1,3,4-trinitropyrazole, was obtained by N-nitration of 3,4-dinitropyrazole. 1,3,4-Trinitropyrazole enters the ce-substitution reaction of N-nitro group under the action of O-, N-, and C-nucleophyls under mild conditions. Thus, general method of synthesis of 5-substituted 3,4-dinitropyrazoles containing free NH fragment was worked out.