Zirconocene catalyzed synthesis of 2-substituted benzimidazole derivatives

摘要

Zirconocene dichloride (Cp2ZrCl2) in the presence of ethanol is found to be a highly efficient catalyst for the one-pot synthesis of structurally diverse 2-substituted benzimidazole derivatives by reaction of o-phenylenediamine and aromatic aldehydes at ambient temperature.