Point mutations in TP53 but not in p15(Ink4b) and p16(Ink4a) genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma

Magalhaes Marcelo; Oliveira Pedro D.; Bittencourt Achilea L.; Farre Lourdes

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Point mutations in TP53 but not in p15(Ink4b) and p16(Ink4a) genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma

机译：TP53中的点突变而不是p15（Ink4b）和p16（Ink4a）基因中的点突变代表急性成人T细胞白血病/淋巴瘤的不良预后因素

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《Leukemia and lymphoma》 |2015年第12期|共3页
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Magalhaes Marcelo; Oliveira Pedro D.; Bittencourt Achilea L.; Farre Lourdes;
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中图分类肿瘤学;
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1. Point mutations in TP53 but not in p15(Ink4b) and p16(Ink4a) genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma [J] . Magalhaes Marcelo, Oliveira Pedro D., Bittencourt Achilea L., Leukemia and lymphoma . 2015,第12期

机译：TP53中的点突变而不是p15（Ink4b）和p16（Ink4a）基因中的点突变代表急性成人T细胞白血病/淋巴瘤的不良预后因素
2. Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study. [J] . Kim M, Yim SH, Cho NS, Cancer genetics and cytogenetics . 2009,第1期

机译：CDKN2A（p16，p14）和CDKN2B（p15）基因的纯合缺失是成人的不良预后因素，但在儿童B系急性淋巴细胞白血病中却并非如此：比较缺失和甲基化研究。
3. Ikaros family zinc-finger 1 mutation is an independent factor for the poor prognosis of adult B-cell acute lymphoblastic leukemia, and allogeneic hematopoietic stem cell transplantation can improve clinical outcomes [J] . Tang Shanhao, Shen Hongjie, Qu Changju, Bone marrow transplantation . 2019,第2期

机译：Ikaros Family Zinc-Finger 1突变是成人B细胞急性淋巴细胞白血病预后不良的独立因素，同种异体造血干细胞移植可以改善临床结果
4. PHOSPHOLIPIDS' SERA AND MONONUCLEAR CELLS IN ACUTE LEUKEMIA, MALIGNANT LYMPHOMA AND MULTIPLE MYELOMA-EVALUATION BY ~(31)P MRS IN VITRO [C] . M. KULISZKIEWICZ-JANUS, B. BACZYNSKI NATO advanced research workshop on magnetic resonance in colloid and interface science . 2002

机译：磷脂的血清和单核细胞在急性白血病，恶性淋巴瘤和多发性骨髓瘤 - 评估中由〜（31）PRS体外
5. The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics [D] . Smith, Kaitlyn Hill. 2021

机译：血红素调节抑制途径调节预后不良B族急性白血病至BH3 - 模拟物的易感性
6. TP53 and p16INK4A mutations in adult-T cell leukemia/lymphoma (ATL) in Bahia (Brazil) [O] . Marcelo Magalhães, Marco A Salvino, Achilea Bittencourt, 2011

机译：巴西巴伊亚州成人T细胞白血病/淋巴瘤（ATL）中的TP53和p16INK4A突变
7. p16/INK4a and p15/INK4b Gene Methylation and Absence of p16/INK4a mRNA and Protein Expression in Burkitt's Lymphoma [O] . Ulf Klangby, Ismail Okan, Kristinn P. Magnusson, 1998

机译：p16 / ink4a和p15 / ink4b基因甲基化和缺乏p16 / ink4a mRNA和Burkitt淋巴瘤的蛋白质表达

Point mutations in TP53 but not in p15(Ink4b) and p16(Ink4a) genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma

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