Prostate cancer: The androgen receptor - A novel target for vaccines

摘要

The androgen receptor is a potential target for prostate cancer vaccines, according to a research group from Wisconsin, USA. Olson et al. used several rodent models to demonstrate the efficacy of a DNA vaccine (pTVG-AR) that targets the androgen receptor ligand-binding domain, which demonstrates high levels of intraspecies and interspecies sequence homology.