Syntheses of compounds with potential anticancer activity. I. Preparative synthesis of N-substituted phenylisoserine derivatives and their reaction with adamantanol

摘要

The preparative method of synthesis of N-substituted phenylisoserine derivatives containing fragments of certain taxane preparations which are important for the manifestation of physiological activity is described. A method of synthesis of adamantly ester of N-benzoylphenylisoserine is developed, which is a model reaction for producing compounds possessing potential anticancer activity.