Frequency of the 35delG Mutation of the Connexin 26 Gene (GJB2) in Patients with Non-Syndromic Recessive Deafness from Bashkortostan and in Ethnic Groups of the Volga-Ural Region

摘要

Congenital deafness is a relatively common human disorder, occurring in one per 1000 newborns on average Deafness is genetically determined in about half of patients. Of all cases of non-syndromic deafness, 75% are autosomal recessive, 10-15% autosomal dominant, and 10-15% X-linked [1-3].