Fatty fish intake,n-3 fatty acids and self-rated health in middle-aged adults

摘要

Background-Since n-3 fatty acids,abundant in fatty fish,may improve health,we raised the question whether self-reported intake frequency of fatty fish(FF)might be related to the percentage of n-3 fatty acids in serum phospholipids(PL-n-3),and also to self-rated health(H).Design-The study followed a cross-sectional design.Methods-In the cross-sectional Oslo Health Study,PL-n-3 were determined in 121 middle-aged ethnic Norwegians and 102 immigrants from the Indian subcontinent and correlated with FF and H.Logistic regression was used to study the relationship between PL-n-3 and H(dichotomized,i.e.Poor vs.Good health).Results-FF correlated positively with PL20:5n-3(PL-EPA,r= 0.467,p <0.001)and PL22:6n-3(PL-DHA,r = 0.499,p <0.001),and negatively with PL20:4n-6(PL-AA,r =-0.350,p = 0.001).H was positively associated with PL-EPA(r = 0.321,p <0.001)and PL-DHA(r= 0.275;p <0.001),but negatively with PL-AA(r =-0.220,p = 0.001).The odds ratio for reporting Poor vs.Good health was significantly higher in subjects with low levels of PL-EPA(OR = 1.49;95% confidence interval =1.17-1.89,p = 0.001),persisting after adjusting for sex,physical activity,ethnicity and length of education.Conclusion-The intake frequency of fatty fish is related to n-3 fatty acids in the serum phospholipids,and to self-rated health.