Synthesis and Antioxidant Activity of 3-Methoxyflavones

摘要

It is becoming increasingly apparent that the overproduction of reactive oxygen species may overwhelm the protective antioxidative defense mechanisms resulting in oxidative tissue injury.Reactive oxygen species have been implicated in several different diseases including ischemia,inflammation and cancer.Fortunately,plants contain a wide variety of free radical scavenging molecules such as flavonoids,anthocyanins,carotenoids,dietary glutathione,vitamins and endogenous metabolites.Such natural products are rich in antioxidant activities.Recently,important biological property of natural flavonoids was suggested mainly due to their antioxidant activity elicited by scavenging oxygen radicals and inhibiting peroxidation.Also,the antioxidant activity of the flavonoids varies considerably depending on the backbone structures and functional groups.