Mediastinal teratomas are typically benign and asymptomatic, but they undergo sudden enlargement or rupture into neighboring organs in some patients owing to intratumoral hemorrhage, leading to serious complications. We report the case of a mediastinal mature teratoma that was discovered because of the sudden onset of chest pain accompanied by elevated preoperative serum CA19-9 levels. The patient was a 43-year-old man who experienced sudden chest pain and was brought to hospital in an ambulance. Chest radiography and computed tomography revealed a mediastinal tumor and a serum CA19-9 level that was elevated to 4377 U/ml. The tumor comprised soft tissue, fluid, and cystic components. The histological diagnosis was mature teratoma with peritumoral bleeding. Most epithelial components, including squamous epithelium and similar components in the bronchi, showed positive results for CA19-9 on immunohistological examination. The postoperative course was uneventful, and serum CA19-9 levels normalized.
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机译:纵隔畸胎瘤通常是良性和无症状的,但由于肿瘤内出血,它们在某些患者中会突然肿大或破裂进入邻近器官,从而导致严重的并发症。我们报告了一个纵隔成熟畸胎瘤的病例,该病例是由于突然发作的胸痛并伴有术前血清CA19-9水平升高而被发现的。该患者是一名43岁的男子,经历了突然的胸痛,并被救护车送往医院。胸部X线和计算机断层扫描显示纵隔肿瘤和血清CA19-9水平升高至4377 U / ml。肿瘤包括软组织,液体和囊性成分。组织学诊断为成熟的畸胎瘤伴肿瘤周围出血。在免疫组织学检查中,大多数上皮成分,包括鳞状上皮和支气管中的类似成分,对CA19-9均显示阳性结果。术后过程平稳,血清CA19-9水平恢复正常。
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