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Tissue expansion for correction of scars due to burn and other causes: A retrospective comparative study of various complications

机译:组织扩张以纠正由烧伤和其他原因引起的疤痕:各种并发症的回顾性比较研究

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Background: Tissue expansion is associated with a relatively high complication rate. The aim of this study was to quantify the complication risk of burn scar patients who underwent tissue expansion in comparison to patients with other indications such as skin tumors. Furthermore it was attempted to compare the complication rates in children and adults. Methods: A retrospective analysis was performed on 148 expanders implanted in 73 patients during the years 1994-2011. Two patient cohorts (burn scar cohort n = 31 and other indication cohort n = 42) were identified and analyzed. Results: 27 male and 46 female patients with a median age of 21 years were included. No statistically significant difference for complication risk between the burn and other indication cohorts could be found (p = 0.1412). Statistical analyses revealed a higher complication rate (52%) in the lower limb compared to all other anatomic sites (29%) (p = 0.1746). In addition, statistical analyses revealed a significantly higher total complication rate in children younger than 10 years (p = 0.0043). Moreover a greater TBSA was accompanied by a higher complication rate (p = 0.0258). Conclusion: This set of data suggests that the burn scar patient is at no greater risk to suffer complications from tissue expansion. Other factors like age, TBSA and anatomical site have far more influence on the expander complication rate than the initial indication for tissue expansion.
机译:背景:组织扩张与较高的并发症发生率相关。这项研究的目的是量化与具有其他适应症(例如皮肤肿瘤)的患者相比,经历组织扩张的烧伤疤痕患者的并发症风险。此外,尝试比较儿童和成人的并发症发生率。方法:回顾性分析1994-2011年间在73例患者中植入的148支扩张器。确定并分析了两个患者队列(烧伤疤痕队列n = 31,其他适应症队列n = 42)。结果:包括27例男性和46例女性,中位年龄为21岁。在烧伤和其他适应证人群之间,未发现并发症风险的统计学显着性差异(p = 0.1412)。统计分析显示,与所有其他解剖部位(29%)相比,下肢的并发症发生率更高(52%)(p = 0.1746)。此外,统计分析表明,10岁以下儿童的总并发症发生率明显更高(p = 0.0043)。此外,更大的TBSA伴有更高的并发症发生率(p = 0.0258)。结论:这组数据表明烧伤疤痕患者没有更大的组织扩张并发症风险。年龄,TBSA和解剖部位等其他因素对扩张器并发症发生率的影响远大于组织扩张的最初指征。

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