Diffuse large B-cell lymphoma with Dutcher bodies.

摘要

A 61-yr-old female patient was diagnosed with stage IVB diffuse large B-cell lymphoma (DLBCL) and received six cycles of R-CHOP. She had initial response, but was found to have enlarged mammary lymph nodes and several erythematous skin nodules on her left thigh 1 yr after treatment. Biopsies of the skin nodules showed a dense lymphoid infiltrate extending from the deep dermis to the subcutaneous tissue, which spared the epidermis. The infiltrate was composed of medium to large cells with round to irregular nuclei, vesicular chromatin and a moderate amount of cytoplasm (Fig. 1A).