Effect of different frequencies of endurance training on antioxidant defense in non-athletes after exhaustive exercise

摘要

Objective: We investigated the effects of endurance training with different frequencies on the blood antioxidant enzymes activities and indexes of lipid, protein and DNA damage after exhausted exercise. Methods: 30 non-athlete healthy subjects were divided into two experimental groups (A and B) and one control group (C), involving 10 people in each group. All groups underwent Bruce test. Then experimental groups were subjected to five-week endurance training with different frequencies. All groups underwent treadmill exercise for the second time 72 hour after last week. After each Bruce test, blood sampling was obtained from capital vein for biochemical measurements. Results: In groups A and B, antioxidant enzyme activities and the levels of oxidative damage biomarkers after endurance training were significantly higher than before training condition. After endurance training, higher enzyme activities were found in groups A, B, followed by C. The levels of oxidative damage biomarkers in group A and B after endurance training were significantly higher as compared with control group. The lowest levels of these indexes were related to control group. Conclusions: This study suggests that high and low training frequencies increases the antioxidant enzyme activities and the levels of oxidative damage biomarkers. However, increase in antioxidant enzyme activities is more remarkable in high frequency training.