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Failure following revision total knee arthroplasty: infection is the major cause.

机译:翻修全膝关节置换术后失败:感染是主要原因。

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摘要

The objective of this study was to evaluate the survivorship of revision TKA and determine the reasons and predictors for failure. Between January 1999 to December 2005, 499 total knee arthroplasty revisions were performed on 474 patients. There were 292 (61.6%) women and 182 (38.4%) men. The average age at the time of index revision was 63.9 years. Revision was defined as surgery in which at least one component (tibial, patellar, femoral, or polyethylene) required exchange. At an average follow-up of 64.8 months (range, 24.1-111.6), and considering reoperation or re-revision as failure, there were 102 failures (18.3%). Infection was the major cause of failure (44.1%) followed by stiffness (22.6%), patellar or extensor mechanism problems (12.8%), periprosthetic fracture (5.9%), loosening (4.9%), haematoma formation (3.9%), malalignment (2.9%), and instability (2.9%). A total of 83% of failures were early (less than two years). Infection was the most common mechanism of failure of revision TKA. The majority of TKA revision failures tend to occur in the first two years after revision. The mode of failure of revision TKA appears to differ from the failure of primary TKA to some extent. Better understanding of current modes by which TKA revisions fail may enable surgeons to prevent these problems and improve outcomes for revision TKA.
机译:这项研究的目的是评估修订版TKA的存活率,并确定失败的原因和预测因素。从1999年1月至2005年12月,共对474例患者进行了499次膝关节置换术。有292名(61.6%)妇女和182名(38.4%)男性。指数修订时的平均年龄为63.9岁。修订定义为需要更换至少一种成分(胫骨,pa骨,股骨或聚乙烯)的手术。平均随访64.8个月(范围24.1-111.6),并将重新手术或重新修订视为失败,发生了102例失败(18.3%)。感染是失败的主要原因(44.1%),其次是僵硬(22.6%),pa骨或伸肌机制问题(12.8%),假体周围骨折(5.9%),松弛(4.9%),血肿形成(3.9%),错位(2.9%)和不稳定(2.9%)。总共83%的故障是早期的(不到两年)。感染是修订版TKA失败的最常见机制。大多数TKA修订失败往往发生在修订后的前两年。修订版TKA的失败模式似乎与主要TKA的失败有所不同。更好地了解TKA修订失败的当前模式可以使外科医生预防这些问题并改善TKA修订的结果。

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