Sebaceous glands in the uterine cervix and vaginal wall: congenital misplacement, metaplastic process, or both?

摘要

I read with great interest the letter to the editor commenting on the topic of ectopic skin-like adnexal structures, including sebaceous glands and hair follicles in the uterine cervix (1). The researchers concluded that the metaplastic theory was not the most likely explanation for the development of piloseba-ceous unit, and favor the congenital misplacement theory. At around the same time, I was encountering 2 cases of sebaceous metaplasia, 1 each in the cervix and vaginal wall. A 48-year-old female patient presented for an adnexal mass and pelvic pain. A total hysterectomy, salpingo-oophorectomy, and staging biopsies were carried out with a diagnosis of ovarian low-grade serous carcinoma. A random section of the uterine cervix yielded a focus of sebaceous metaplasia (Figs. 1A, B). Additional sections failed to discover other foci.