Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors

Krause Guenter; Baki Imaan; Kerwien Susan; Knoedgen Eva; Neumann Lars; Goeckeritz Elisa; Landwehr Thomas; Heider Karl-Heinz; Hallek Michael

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Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors

机译：CD37抗体BI 836826与化学治疗剂或PI3K抑制剂联合对慢性淋巴细胞性白血病细胞的细胞毒性

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来源
《British Journal of Haematology》 |2016年第5期|共4页
作者
Krause Guenter; Baki Imaan; Kerwien Susan; Knoedgen Eva; Neumann Lars; Goeckeritz Elisa; Landwehr Thomas; Heider Karl-Heinz; Hallek Michael;
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正文语种 eng
中图分类血液及淋巴系疾病;
关键词
chronic lymphocytic leukaemia; monoclonal antibodies; CD37; direct cell death; drug combinations;

机译：慢性淋巴细胞白血病;单克隆抗体;CD37;直接细胞死亡;药物组合;

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1. Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors [J] . Krause Guenter, Baki Imaan, Kerwien Susan, British Journal of Haematology . 2016,第5期

机译：CD37抗体BI 836826与化学治疗剂或PI3K抑制剂联合对慢性淋巴细胞性白血病细胞的细胞毒性
2. Combination of two anti-CD5 monoclonal antibodies synergistically induces complement-dependent cytotoxicity of chronic lymphocytic leukaemia cells [J] . KlitgaardJ.L., KoefoedK., GeislerC., British Journal of Haematology . 2013,第2期

机译：两种抗CD5单克隆抗体的组合协同诱导慢性淋巴细胞白血病细胞的补体依赖性细胞毒性
3. Cytotoxic effects of the trifunctional bispecific antibody FBTA05 in ex-vivo cells of chronic lymphocytic leukaemia depend on immune-mediated mechanism. [J] . Boehrer S, Schroeder P, Mueller T, Anti-cancer drugs . 2011,第6期

机译：三功能双特异性抗体FBTA05在慢性淋巴细胞白血病的离体细胞中的细胞毒作用取决于免疫介导的机制。
4. Efficiency and Toxmcity of the Fludarabine and Cyclo- Phosphamide Combined Therapy in Relapsed/ Resistant Patients with B-cell Chronic Lymphocytic Leukaemia (CLL)-Polish Multicenter Study [C] . M. Kowal, A. Dmoszynska, D. Jawniak, European Haematology Association . 2002

机译：B-Cell慢性淋巴细胞白血病（CLL） - 渗透多中心研究的复发/抗性患者复发/抗性患者的氟氮胺碱和环磷酰胺联合治疗的效率和毒性
5. Therapeutic Effect of Adenovirus- and alpha-fetoprotein Promoter-mediated tBid and Chemotherapeutic Agents in Combination on Orthotopic Hepatocellular Carcinoma in Mice. [D] . Ma, Shihong. 2010

机译：腺病毒和甲胎蛋白启动子介导的tBid和化学治疗剂联合治疗对小鼠原位肝细胞癌的治疗作用。
6. Idelalisib improves CD37 antibody BI 836826 cytotoxicity against chemo-resistant /relapse-initiating CLL cells: a rationale for combination treatment [O] . S Betrian, L Ysebaert, K H Heider, 2016

机译：依达拉西布改善CD37抗体BI 836826对化学抗性/复发型CLL细胞的细胞毒性：联合治疗的基本原理
7. Correction to: Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B cell non-Hodgkin lymphoma [O] . Frank Kroschinsky, Jan Moritz Middeke, Martin Janz, 2020

机译：对复发或难治性B细胞非霍奇金淋巴瘤的患者中BI 836826（CD37抗体）的校正校正DOSE升级研究

Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors

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