Objective :Urinary tract infection is a common clinical entity which is encountered in all forms of clinics in patients of all ages. Every geographical area has been a specific pattern of infecting micro-organism and a peculiar antibiogram which tend to change with time and place. Micro-organisms causing urinary tract infections of yesterday which were sensitive to commonly used drugs no longer exhibit the old sensitivity pattern today. The exact knowledge of bacteriology and sensitivity pattern is mandatory for accurate and Cost effective treatment of urinary tract infections. Materials and Methods : A total of 914 (360 males and 554 females) subjects having sign and symptoms of urinary tract infection were selected from clinical wards of the Nalanda Medical College and Hospital, Patna. Clean catch mid stream urine of above subjects were collected and physical and microscopic examination, culture and biochemical tests were performed for identification of micro-organisms responsible for urinary tract infections. A total of 200 pathogens were isolated and treated against different antimicrobials by modified Kirby- Bauer method. Result: Out of 200 isolates the most Common micro-organism was Escherichia coli (58%) followed by Klebsiella spp. (13.5%) Pseudomonas aeruginosa (4.5%) Citrobacter (4.5%), Proteus Spp.(3.5%) Staphylococcus aureus (3.5%) and Candida albicans (1.5%), Acinatobacter, Staphylococcus saprophyticus, streptococci, enterobacter were responsible for 15% of Urinary tract infections. Among all treated antimicrobials piperacillin was most effective drug inhibiting 92.2% of isolates followed by azetronam (82.4%), ceftriaxone +salbactum (77.3%) and amikacin (73.1%). ampicillin was least sensitive antimicrobial which inhibited only (1.03%) of total isolates. Conclusion : Most common pathogen responsible for Urinary tract infection in was Escherichia coli. Newer drug...
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