Use of polyfunctionalized ethylene synthons: Convenient synthesis of biologically active trifluoromethyl containing N-substituted-benzoylpyrazoles and triazole

摘要

Ten biologically active trifluoromethyl containing N-substituted-benzoylpyrazoles (3a-d,4a-d,and 6a,b) and one triazole analogue 5 have been conveniently synthesized from four versatile polyfunctionalized ethylene synthons and one novel synthon N-cyanoimido-S,S- dimethyldithio-carbonale (CIDT,nu),respectively.The reactions of trifluoromethyl containing substituted benzoylhydrazine with classical synthons such as ethyl dimethylaminomelhylene- malonate,acetylacelone and ethyl acetoacetate have also been investigated.Hcrbicidal,fungicidal and plant-growth regulation activities for all reported new compounds have been determined and reported.