Synthesis and biological activity of some isoniazid based 1,3,4-oxadiazole derivatives

摘要

1,3,4-Oxadiazole and isoniazid moieties are important because of their versatile biological actions.In the present studies,the oxadiazole system has been built with the isoniazid moiety and a few compounds in this series have been synthe-sised and their antiinflammatory and biological properties studied.In continuation to our work on 1,3,4-oxadiazoles which are biologically an important group of compounds having activities like bactericidal,antifungal,analgesic,antiinflammatory and wheat growth promoters etc.,we now report the synthesis and biological activity of some new isoniazid based oxadiazoles.