Potential Bioprotective Effect of Reuterin Produced By L.reuteri BPL-36 Alone And In Combination With Nisin Against Food Borne Pathogens

摘要

The effect of reuterin alone and in combination with nisin on different Gram-positive and Gramnegative foodbome pathogens in milk as a model system was investigated. Reuterin (16 AU/ml) exhibited bactericidal activity against Listeria monocytogenes, whereas its bactericidal activity against Staphylococcus aureus at 37°C was more pronounced. Higher bactericidal activity was also detected against Escherichia coli 0157:H7, Pseudomanas aeruginosa and Salmonella typhi. The synergistic effect of reuterinand nisin against L. monocytogenes and S. aureus was observed when reuterin was combined with nisin (100 IU/ml). The combination of reuterin with nisin, however, did not enhance the antimicrobial effect of reuterin against Gram-negative pathogens. Milk and milk products treated with natural antimicrobials might serve as a feasible system to control pathogenic contaminants.