The Dance Steps of GenomicsPart I: Understanding Genomic Prediction

摘要

Whenever I hear the words "two-step" my mind goes back to my teenage years when I dancedwith cute girls at the county fair. But, in this article we will be discussing a different type of two-step. There are two common methods, referred to as two-step or one-step, for including genomic (i.e. DNA) information into the genetic evaluations we use to estimate expected progeny differences (EPDs). Two-step genomic predictions use the genomic and pedigree information separately in two different prediction steps. In one-step genomic predictions, genomic and pedigree information is combined and used in a single step.