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Management of difficult infantile haemangiomas

机译:婴儿难治性血管瘤的治疗

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Infantile haemangiomas are common vascular tumours of infancy. They typically present shortly after birth, undergo a period of rapid proliferation, and then slowly involute over many years. Although most patients require no intervention, appropriate investigation and treatment may be necessary in a minority of cases. Identifying which patients require further investigation or intervention can be difficult due to the heterogeneity of clinical presentation. This is compounded by a lack of rigorous randomised controlled trials on haemangioma management. Therefore, the rationale for treatment is not always straightforward. Haemangiomas occur anywhere on the body, have superficial, deep or mixed morphology, and depending on anatomic location, size and subtype, can be associated with underlying structural anomalies and many other potential complications. Generally, the management of difficult haemangiomas is best approached on a case-by-case basis. Over the last few years, there have been several advances in our understanding of haemangiomas, together with some exciting new therapeutic options. In the following review, the authors discuss the various possible complications of infantile haemangiomas, the rationale for treatment and appropriate possible interventions.
机译:婴儿血管瘤是常见的婴儿血管瘤。它们通常在出生后不久出现,经历快速增殖期,然后在多年内缓慢渐开线。尽管大多数患者不需要干预,但在少数情况下可能需要适当的调查和治疗。由于临床表现的异质性,很难确定哪些患者需要进一步调查或干预。缺乏严格的关于血管瘤治疗的随机对照试验使情况更加复杂。因此,治疗的原理并不总是那么简单。血管瘤发生在身体的任何地方,具有浅表,深层或混合形态,并且取决于解剖位置,大小和亚型,可能与潜在的结构异常和许多其他潜在的并发症相关。通常,最好根据具体情况对难治性血管瘤进行处理。在过去的几年中,我们对血管瘤的理解有了一些进步,同时还有一些令人兴奋的新治疗选择。在下面的评论中,作者讨论了婴儿血血管瘤的各种可能的并发症,治疗的原理以及适当的可能干预措施。

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