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Management of infantile haemangioma

机译:婴儿血管瘤的治疗

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Infantile haemangioma (IH) are benign vascular tumours affecting 4-5% of infants. Natural history is of rapid growth in the first few months of life followed by stabilisation and gradual resolution. IH are usually an isolated cutaneous problem. Occasionally they may be associated with internal haemangioma or other abnormalities of cardiovascular and neurological systems. Treatment is required in the first few months of life for IH which are threatening life or function, become ulcerated, or are likely to cause residual problems due to site or large size. First line treatment in most centres is oral propranolol, despite it being unlicensed for this indication. Treatment is continued until 12-16 months of age; there is a small risk of rebound growth after stopping. Other treatments that may be considered in specific situations include oral or intra-lesional steroids, vincristine, pulsed dye laser, embolisation and surgery. A multi-disciplinary approach involving paediatricians, dermatologists and other organ specialists is required to ensure consistent and optimum management for this common condition.
机译:婴儿性血管瘤(IH)是良性血管肿瘤,影响4-5%的婴儿。自然历史在生命的最初几个月中快速增长,然后稳定下来并逐步解决。 IH通常是一个孤立的皮肤问题。有时它们可​​能与内部血管瘤或心血管和神经系统的其他异常有关。 IH在生命的最初几个月中需要进行治疗,这些疾病可能威胁生命或功能,变得溃疡或可能因部位或面积过大而引起残留问题。在大多数中心,一线治疗是口服普萘洛尔,尽管未获得该适应症的许可。治疗持续到12-16个月大。停止后反弹增长的风险很小。在特定情况下可能考虑的其他治疗方法包括口服或病灶内的类固醇,长春新碱,脉冲染料激光,栓塞和手术。需要一种多学科的方法,涉及儿科医生,皮肤科医生和其他器官专科医生,以确保针对这种常见疾病进行一致且最佳的治疗。

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