Obesity measures, metabolic profiles and dietary fattyacids in lean and obese postmenopausal diabetic AsianIndian women

摘要

The present investigation was aimed to compare anthropometric, metabolic anddietary fatty acids profiles in lean and obese postmenopausal diabetic Asian Indian women.A total of 125 postmenopausal Asian Indian women (Group I: lean postmenopausal control,n = 50; Group II: lean postmenopausal diabetic, n = 40 and Group III: obese postmenopausaldiabetic, n = 35) aged 40 years and above were studied. Anthropometric [height, weight,waist (WC) and hip circumference] metabolic [total cholesterol (TC), triglyceride (TG), high(HDL), low density lipoprotein (LDL) and fasting plasma glucose (FPG)] and dietary pro-files were collected from each participant. Body mass index (BMI), waist-hip ratio (WHR)and conicity index (CI) were subsequently computed. Obesity was defined as women havinga BMI ≥ 25 kg/m2. An open-ended 24 h food recall schedule was used to collect nutrientinformation from each participant. Daily intake of nutrients including saturated (SFA),monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA) were also estimated onweekly and monthly basis. Group I had significantly lower mean than both Group II andGroup III for WC, WHR, CI, TC, TG, LDL, FPG and total carbohydrates. On the other hand,Group I had significantly greater mean than both Group II and Group III for UFA/SFA,MUFA/SFA and PUFA/SFA. Discriminant analysis had revealed that overall 88% of all caseswere correctly (positively) classified in three groups using fatty acids and their ratios. Itseems reasonable to argue that while dealing with postmenopausal diabetic women, clini-cians should consider obesity measures, lipids and dietary fatty acids simultaneously to bettercomprehend clinical assessments and risk stratification.