#28 Impact of antidiabetic medications on physical and cognitive functioning of older mexican americans with diabetes mellitus.

摘要

PURPOSE: The current study was designed to evaluate the utility of antidiabetic medications in affecting changes in physical and cognitive functioning among older Mexican Americans diabetic patients over a 2-year period.METHODS: The existing cohort of Mexican Americans 60 or older in the Sacramento Area Latino Study on Aging (SALSA) Project was used. Physical functioning status was measured by assessment of Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL). Cognitive functioning was measured by the Modified Mini Mental State Exam (3MS) and Delayed Word-list Recall Test. A generalized estimating equation (GEE) was used for data analysis.RESULTS: A total of 718 diabetic subjects in SALSA were divided into two groups (based on the duration of diabetes) to examine the effect of antidiabetic medications. For subjects with diagnosed diabetes