Development of a Reconstructed Human Skin Model in Vitro for Screening Formulas on Alleviating Infant Atopic Eczema

摘要

[Purpose] It has been reported that thymic stromal lympho-poietin (TSLP) increase was one of the causes of atopic eczema. In this study, an eczema-like skin model was used to select the effective formulations by testing thymic stromal lymphopoietin (TSLP) value and skin barrier parameter time-to-toxicity (ET50， time taken to reduce the viability to the cells by 50%).