Intra-arterial injection of human adipose-derived stem cells improves viability of the random component of axial skin flaps in nude mice

摘要

Background: Skin flap necrosis is a common postoperative complication in reconstructive surgery. Recent evidence suggests that subcutaneously injected adipose-derived stem cells (ASCs) increase the viability of random skin flaps. Here, we examined whether intraarterial human ASC administration could improve random component survival of axial skin flaps in nude mice.