Successful Treatment of Mediastinal gamma delta T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation

摘要

A 3-year-old girl presenting with a huge mediastinal tumor and massive pleural effusion, was diagnosed with stage III T-cell lymphoblastic lymphoma ( T-LBL) by flow cytometry of effusion cells. Four courses of chemotherapy achieved complete remission, and 5/6 HLA allele-matched cord blood transplantation was performed with success. The patient remains in first complete remission 16 months after transplantation. T-LBL is very rare, especially that of mediastinal origin, and is acknowledged as having an extremely poor clinical outcome. The present case study is the first to report the successful treatment of mediastinal T-LBL in a toddler.