Evaluation of ELISA and CLIA for Treponema pallidum specific antibody detection in China: A multicenter study

Ji Huimin; Chang Le; Zhao Junpeng; Zhang Lu; Jiang Xinyi; Guo Fei; Wang Lunan

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Evaluation of ELISA and CLIA for Treponema pallidum specific antibody detection in China: A multicenter study

机译：对中国蛋白酶磷酸盐磷酸盐菌特异性抗体检测的评价：多中心研究

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Background: Considering the rapid increase of syphilis infections in several countries including China, searching for a screening test with sufficient sensitivity and specificity is extremely urgent. The current study mainly researched the performance for Treponema pallidum (TP) detection by electro-chemiluminescence immunoassays (ECLIA), chemiluminescence immunoassays (CLIA) and four commercially available ELISA assays commonly used in China.

机译：背景：考虑到在包括中国在内的若干国家的梅毒感染的快速增加，寻找具有足够敏感性和特异性的筛查测试是非常紧迫的。目前的研究主要研究了通过电化学发光免疫测定（Eclia），化学发光免疫测定（CLIA）和中国常用的四种市售ELISA测定的蛋白质磷脂（TP）检测的性能。

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来源
《Journal of Microbiological Methods》 |2019年第2019期|共6页
作者
Ji Huimin; Chang Le; Zhao Junpeng; Zhang Lu; Jiang Xinyi; Guo Fei; Wang Lunan;
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作者单位

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

Beijing Hosp Natl Ctr Gerontol Natl Ctr Clin Labs 1 Dahua Rd Beijing 100730 Peoples R China;

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正文语种 eng
中图分类微生物研究与微生物实验;
关键词
Treponema pallidum specific antibody; Electro-chemiluminescence immunoassays (ECLIA); Chemiluminescence immunoassays (CLIA); ELISA;

机译：Treponema pallidum特异性抗体;电化学发光免疫测定（Eclia）;化学发光免疫测定（CLIA）;ELISA;

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1. Evaluation of ELISA and CLIA for Treponema pallidum specific antibody detection in China: A multicenter study [J] . Ji Huimin, Chang Le, Zhao Junpeng, Journal of Microbiological Methods . 2019,第期

机译：对中国蛋白酶磷酸盐磷酸盐菌特异性抗体检测的评价：多中心研究
2. Evaluation of a Treponema pallidum-specific IgM enzyme immunoassay and Treponema pallidum western blot antibody detection in the diagnosis of maternal and congenital syphilis. [J] . Rawstron SA, Mehta S, Bromberg K Sexually transmitted diseases . 2004,第2期

机译：评价梅毒螺旋体特异性IgM酶免疫法和梅毒螺旋体Western blot抗体检测对母体和先天性梅毒的诊断。
3. Evaluation of a colloidal gold immunochromatography assay in the detection of Treponema pallidum specific IgM antibody in syphilis serofast reaction patients: a serologic marker for the relapse and infection of syphilis. [J] . Lin LR, Tong ML, Fu ZG, Diagnostic microbiology and infectious disease . 2011,第1期

机译：胶体金免疫层析法在梅毒血清反应快速患者中检测梅毒螺旋体特异性IgM抗体的评估：梅毒复发和感染的血清学标志物。
4. EVALUATION OF THE SENSITIVITY, SPECIFICITY AND TIME POST INFECTION FOR DETECTION OF TGE ANTIBODIES USING TWO COMMERCIAL BLOCKING ELISA ASSAYS COMPARED TO THE SERUM NEUTRALIZATION ASSAY [C] . E Cornaglia, I Moreau Congress of the International Pig Veterinary Society . 2002

机译：与血清中和测定相比，使用两种商业阻断ELISA测定检测TGE抗体的感染后敏感性，特异性和时间后的感染后敏感性，特异性和时间
5. EPIDEMIOLOGY OF SWINE DYSENTERY: DEVELOPMENT AND EVALUATION OF CULTURAL AND SEROLOGICAL METHODS FOR THE DETECTION OF TREPONEMA HYODYSENTERIAE INFECTION. [D] . SONGER, JOSEPH GLENN. 1976

机译：猪痢疾的流行病学：用于检测丙型肝炎性小肠痢疾感染的文化和血清学方法的发展与评估。
6. Performance Evaluation of CLIA for Treponema Pallidum Specific Antibodies Detection in Comparison with ELISA [O] . Lixin Li, Bei Cai, Chuanmin Tao, 2016

机译：与ELISA相比CLIA检测梅毒螺旋体特异性抗体的性能评估
7. Multicenter evaluation of EIAs and CLIAs in the detection of hepatitis C virus antibody among blood donors in China [O] . Le Chang, Huimin Ji, Fei Guo, 2020

机译：中国献血者丙型肝炎病毒抗体检测中的艾萨斯和克拉族的多中心评价
8. Studies on in vitro Cultivation of 'Treponema pallidum'. [R] . fieldsteel, a. howard miao,raymond 1979

机译：“梅毒螺旋体”离体培养的研究。

Evaluation of ELISA and CLIA for Treponema pallidum specific antibody detection in China: A multicenter study

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