Comparison Between Linked Color Imaging and Blue Laser Imaging for Improving the Visibility of Flat Colorectal Polyps: A Multicenter Pilot Study

摘要

Introduction Linked color imaging (LCI) and blue laser imaging-bright (BLI-b) improve the visibility of gastrointestinal lesions. In this multicenter study, we compared the effects of LCI and BLI-b on the visibility of flat polyps with visibility scores and color difference (CD) values, including fast-withdrawal and large-monitor observation. Methods We recorded 120 videos of 40 consecutive flat polyps (2-20 mm), adenoma, and sessile serrated adenoma and polyp (SSA/P), using white light imaging (WLI), BLI-b, and LCI from July 2017 to December 2017. All videos were evaluated by eight endoscopists according to a published polyp visibility score of 4 (excellent) to 1 (poor). Additionally, 1.5 xfaster and 1.7 xsized videos were evaluated. Moreover, we calculated the CD values for each polyp in three modes. Results The mean LCI scores (3.1 +/- 0.9) were significantly higher than the WLI scores (2.5 +/- 1.0,p < 0.001) but not significantly higher than the BLI-b scores (3.0 +/- 1.0). The scores of faster videos on LCI (3.0 +/- 1.1) were significantly higher than WLI (2.0 +/- 1.0,p < 0.001) and BLI-b (2.8 +/- 1.1,p = 0.03). The scores of larger-sized videos on LCI were not significantly higher than those of WLI or BLI-b. The CD value of LCI (18.0 +/- 7.7) was higher than that of WLI (11.7 +/- 7.0,p < 0.001), but was not significantly higher than that of BLI-b (16.6 +/- 9.6). The CD value of LCI was significantly higher than that of BLI-b for adenoma, but the CD value of BLI-b was significantly higher than that of LCI for SSA/P. Conclusions The superiority of LCI to BLI-b was proven for the visibility of adenoma and fast observation.