Synthesis, crystal structure and antimicrobial activities of a dinuclear silver(I) complex of bis(diphenylphosphano)methane and thiourea

摘要

A heteroleptic silver(I) complex of bis(diphenylphosphano)methane (DPPM) and thiourea (tu) with the formula [Ag-2(DPPM)(2)(tu)(3)](NO3)(2)center dot 2H(2)O (1) was prepared and characterized by infrared (IR) and nuclear magnetic resonance ((1) H, C-13, and P-31) spectroscopic methods, and X-ray crystallography. The crystal structure determination has shown that the complex (1) is dinuclear having each silver(I) ion coordinated by two phosphorus atoms of DPPM molecules and two sulfur atoms of tu ligands adopting a distorted tetrahedral environment. The two silver atoms are bridged by one of the three tu molecules. The other two tu ligands are coordinated in a terminal mode; one with each silver(I) ion. The dinuclear units are associated to each other through hydrogen bonding interactions to form a three-dimensional network in the solid state. Complex 1 showed significant activity against two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), and molds (Aspergillus niger, Penicillium citrinum), while the activities were poor towards yeasts (Candida albicans, Saccharomyces cerevisiae).