Synthesis, Crystal structure and antimicrobial activity of a mixed-iigand copper (II) complex Cu(pht)_2 (phen)H_2O

摘要

A novel mixed-ligand copper(II) complex [Cu(pht)2(phen)H_2O] (Hpht = 5,5-diphenylimidazolidine-2,4-dione, phen = 1,10-phenanthroline) was has been synthesized solvent-thermally and characterized by elemental analysis, IR and single-crystal X-ray diffraction. The crystal of the copper complex belongs to Triclinic system with space group P_1, a = 11.747(14), b = 12.639(15), c = 14.021(17)A, a= 97.986(18)°,β= 104.958(18) °, γ= 108.485(19) °,V= 1851(4) A~3, D_c= 1.371 g/cm~3,Z= 2,F(000) = 790,μ = 0.644mm~(-1),R_1, =0.0835, wR_2 = 0.1436 [I>2σ(I)] and GOF =0.867. The X-ray data showed that the Cu(IJ) atom adopted a distorted CuN_2O_3 square pyramidal configuration when coordinated with two phen ligands and one water ligand. The antimicrobial activity of the title complex was evaluated against a series of fungi or bacteria in vitro by agar methodand the filter paper method, respectively . The results showed that the title complex was more active against the Fusarim gramine arum, Escherichia coli and Staphylococcus Aureus than its precursor Hpht and Cu(Ac)_2-H_2O.