Spice-Rack Chromatography: Going Beyond Salt and Pepper to Optimize Purification and Separation

摘要

Selecting the best stationary phase to purify or separate a compound can be a struggle. Typically, bench chemists simply use whatever stationary phase is handy in their laboratory, or work with whatever their predecessors used. It's much wiser to think like a chef and consider the full "spice rack" of stationary phases now available. LCGC recently sat down with David Schurer, executive vice president/co-founder & partner at Sorbent Technologies, Inc., to explore why thinking beyond "salt and pepper" when choosing a stationary phase is the best recipe for achieving accurate results: resolution, purity, yield, kinetics, and cost.