Quinazoline addition to indole hydrazone derivatives in TFA as a facile synthesis of trifluoroacetylhydrazide quinazoline sigma-adducts

摘要

Addition of indole 3-carbaldehyde arylhydrazones to quinazoline in trifluoroacetic acid occurs at the C-5-atom of the indole moiety affording quinazoline sigma-adducts with indole and trifluoroacetylhydrazide moieties.