The gene spectrum of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Guangdong province, China

摘要

Background: G6PD deficiency presents a higher incidence rate in southern China. Many variants of G6PD resulted from point mutations in the G6PD gene, which lead to decrease of enzyme activity. The objective of this study was to analyze the genotype of G6PD deficiency in four regions of Guangdong province.