Malignant paraganglioma and somatotropinoma in a patient with germline SDHB mutation—genetic and clinical features

摘要

Pituitary adenomas and paragangliomas/pheocromocytomas are rare endocrine tumours, which can be sporadic or familial. During many years their coexistence in the same individual was considered a coincidental finding. However, an association between these two entities was recently demonstrated, with the possible involvement of SDHx genes.